Synergism - Occurs when the effect of two drugs together is greater than the effect of either along, Antagonism - Occurs when the effect of two drugs together is less than the effect of either along, Antacids - increases the pH of the stomach, Enterococcus faecium - the first E of the ESKAPE pathogens, S aureus - the S of the ESKAPE pathogens, K pneumoniae - the K of the ESKAPE pathogens, A baumannii - the A of the ESKAPE pathogens, P aeruginosa - the P of the ESKAPE pathogens, E spp - the last E of the ESKAPE pathogens, Ergosterol - the sterol found in fungi, Aplastic anemia - serious side effect of chloramphenicol, Rifamycin - Inhibits RNA synthesis/antituberculosis, Nikkomycin Z - treats with Coccidioidomycosis (Valley Fever) and Yeast infections, Imidazoles - fungicide that disrupts ergosterol biosynthesis for fungal skin infections and vaginal yeast infections, Resistance - Efflux pump, Blocked penetration, Inactivation of enzymes, target modification are examples of _____ to antimicrobial drugs, Oxazolidinones - new class of antibiotics developed in response to vancomycin resistance, Streptomyces - genus of soil bacteria that produce a large number of different antibiotics, Natural Penicillin - Penicillin G and Penicillin V are examples of what, Isoniazid - antibiotic that interferes with the synthesis of mycolic acid, First generation - generation of B-lactams that are narrow spectrum; acts against gram+ bacteria, Second generation - generation of B-lactams that are extended spectrum includes gram- bacteria, Third generation - generation of B-lactams that includes pseudomonads; injected, Fourth generation - generation of B-lactams that is oral, Fifth generation - generation of B-lactams that is active against methicillin-resistant Staphylococcus aureus (MRSA), B-Lactam Ring - Penicillins, cephalosporins, monobactams, and carbapenems all contain what?, Compound 606 - Paul Ehrlich’s discovery that treats syphilis,

Session 10/5/22

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