1) action potential enters from adjacent cell. a) step 2 b) step 1 c) step 9 d) step 10 2) Voltaged-gated Ca2 + channels open. Ca2+ enters cell. a) step 1 b) step 2 c) step 3 d) step 4 3) Ca2+ induced Ca2+ release through ryanodie receptors- channels a) step 3 b) step 5 c) step 6 d) step 8 4) local release causes ca2+ spark a) step 4 b) step 2 c) step 5 d) step 8 5) summed ca2+ spark created a Ca2+ signal. a) step 6 b) step 7 c) step 5 d) step 9 6) Ca2+ ions bind to troponin to imitate contraction a) step 5 b) step 6 c) step 8 d) step 2 7) relaxation occurs when Ca2+ unbind from troponin. a) step 7 b) step 10 c) step 1 d) step 5 8) Ca2+ is pumped back into the sarcoplasmic reticule for storage. a) step 8 b) step 9 c) step 6 d) step 7 9) ca2+ is exchanged with Na+ by NCX antiporter. a) step 9 b) step 10 c) step 2 d) step 8 10) Na+ gradient is maintained by the Na+ - K+ ATPase. a) step 10 b) step 9 c) step 8 d) step 7

EC coupling in cardiac muscle

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