Absorption - The movement of drug from the site of administration to the circulation, Distribution - The transfer of drug to different areas and tissues of the body, First Pass Metabolism - The metabolism of a drug before it reaches the systemic circulation, Half-Life - Time taken for the maximum plasma concention to reduce by half, Receptor agonist - - A drug that binds to and activates a receptor, Receptor antagonist - A drug that binds to a receptor and blocks other drugs, Pharmacokinetics - What the body does to the drug, Pharmacodynamics - Drug mode of action on the body, Cytochrome P450 - A group of enzymes in the liver which are involved in drug metabolism, Excretion - The process of removing waste products from the body, Metabolism - The chemical alteration of a drug by the body, Route of administration - The method by which a drug is taken in to the body, Substrate - A molecule acted on by an enzyme, Chemotherapy drugs - Drugs that interfere with cell growth and and division, Narrow therapeutic index - Drugs where small differences in dose or blood concentration may lead to toxicity or lack of therapeutic action, Pharmacogenomics - How genes affect a person's response to drugs, single nucleotide polymorphisms - genomic variant at a single base position in the DNA, human leukocyte antigen - genes in major histocompatibility complexes (MHC),
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Pharmacology Definitions
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