TCA: High risk for suicide with an overdose, only given 1 week of med at a time, Amitriptyline, suffixes -ipramine or -iptyline, with the exception of Doxepin and Amoxapine, Anticholinergic side effects and sedation, SSRI: First line treatment for major depressive disorder and anxiety, Can help with panic disorder, OCD and bulimia nervosa, High risk of serotonin syndrome - remember SHIVERS, Citalopram and Sertraline - main prototypes for depression, Observe for s/sx of hyponatremia - lethargy, abd cramps, diarrhea and nausea, SNRI: Venlafaxine, May cause N/V and anorexia - watch weight, Not indicated for clients with liver and kidney disease - Duloxetine, Works for Major depression, social anxiety disorder and generalized anxiety disorder, MAOI: Washout period indicated before starting other meds, Diet - tyramine contraindicated, can cause HTN crisis, Treats depression that has not responded well to other drug classes, the client must be able to follow a special diet, This med + SSRI or SNRI within 14 days = serotonin syndrome, Tranylcypromine, Isocarboxazid, Phenelzine, Selegiline (TIPS helps remember the common names of meds), Give the client list of food to avoid, including avocados, chocolate, fermented foods and caffeine, All antidepressant meds (compare): Take 2-4 weeks to have full effect, May increase risk of suicide, Taper drug, don't DC abruptly, Atypical Antidepressants: Buproprion, Treats season affective disorder/depression, Don't give to clients with hx of eating disorders, can cause weight loss, Decreases seizure threshold,
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Compare and contrast Depression meds
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