FOOD, DRUG & COSMETIC ACT OF 1938 - First legislation to regulate drug safety, HARRIS - KEFAUVER AMENDEMENTS OF 1962 - First to demand that drugs actually be of some benefit, CONTROLLED SUBSTANCES ACT OF 1970 - Set rules for the manufacture and distribution of drugs considered to have a potential for abuse, FDA AMENDMENTS ACT OF 2007 - Expanded the mission of the FDA to include rigorous oversight of drug safety after a drug has been released for marketing, COMPREHENSIVE ADDICTION & RECOVERY ACT OF 2016 - Provides Funding to combat a nationwide opioid epidemic by addressing the crisis from the multiple approaches, NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY & HEALTH - Identifies drugs that are hazardous for handling and provides instructions for their use, and the use of protective equipment and environmental controls to protect nurses and other health care workers from harm due to exposure,

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