1) Since cholesterol is the precursor of bile acids and bile acids are lost, what is the expected outcome? a) plasma cholesterol increases b) plasma cholesterol decreases c) plasma cholesterol stays the same 2) Which of the following accurately describes the structure of cholesterol? a) 1 (six membered rings) 6 (5 membered rings) and 1 (hydroxyalcohol) b) 5 (six membered rings) 1 (5 membered rin c) 3 (six membered rings) 1 (5 membered rin d) 1 (six membered rings) 3 (5 membered rin 3) Drugs that inhibit cholesterol synthesis are used to treat which of the following a) coronary artery disease b) liver degredation c) insulin deficiency d) acid reflux 4) As a component of the cell membrane, cholesterol is NOT used in which of the following functions a) membrane structure b) communication with exterior receptors c) fluidity d) membrane transport of materials 5) Cholesterol is used to make ______ in the liver a) antigens b) antibiotics c) billiruben d) bile 6) In the liver, what type of cells convert cholesterol? a) lymphocytes b) adipocytes c) hepatocytes d) leukocytes 7) Bile acid sequestrants will ______ the uptake of cholesterol into the cell thereby _________ plasma cholesterol a) increase, decrease b) decrease, increase c) increase, neutralize d) decrease, neutralize 8) Which of the following is NOT a basis for cholesterol supply? a) exogenous sources b) endogenous sources c) endothermic sources 9) It is the first compound approved for lowering total and LDL-cholesterol levels a) Ezetimibe b) Acetylcholinimize c) Citricsystecholine d) succiynlcholine 10) The effects of using EZETIMIBE include all the following EXCEPT: a) This results in a decrease in the delivery of intestinal cholesterol to the liver. b) Increase in cholesterol being absorbed in the lumen c) Hepatic cholesterol stores are reduced d) Clearance or uptake of cholesterol in the blood is 11) During de novo endogenous systems, the limiting enzyme is which of the following? a) Acetyl CoA b) HMGR c) Lipase d) Progesterone 12) Constant levels of blood cholesterol range from __________ during de novo synthesis a) 150-200 b) 50-100 c) 300-600 d) 1-20 13) Statins competitively inhibit a) NADPH b) ATP c) HMGR d) Acetyl CoA 14) In the presence of statins, de novo cholesterol synthesis will a) increase b) decrease

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